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CRANIOFACIAL
RESEARCH CONSULTING
Services offered:
--Experimental
research consulting in craniofacial embryology,
developmental biology, and 3-D imaging and image
analysis to colleagues, as a visiting scientist or
research consultant, on site.
--Short-term or
long-term assistance, on site, in laboratory and
experimental research procedures, as well as 3-D
imaging (microCT, CT, etc.) and analysis of images
for morphometrics, volumetrics, density measurement,
and other purposes.
--Discussion and
teaching/mentoring in such analyses to colleagues
and/or their mentees.
--In-person, visiting
at host’s university or institution, for such
consultation, short- or long-term, domestically or
internationally.
Experience:
(refer to
Francis Smith CV)
--Independent research
consultant since 2019 to a colleague at University
of Colorado Anschutz Medical Campus, School of
Dental Medicine, Dr. Clifton Carey, in his studies
of tooth density and mandibular bone density, by
assisting and performing 3-D imaging by microCT and
analysis of images for density analysis
--November 2017:
visited Hospital for Rehabilitation of Craniofacial
Anomalies in Bauru, Brazil, and assisted colleagues
Dr. Ivy Trindade-Suedam and Dr. Inge Trindade in
their study of upper airway obstruction in Treacher
Collins. Performed analysis of CT images of patients
with TCS for volumetric and morphological assessment
of upper airway in TCS.
--Experience in
craniofacial 3-D imaging and morphometrics,
volumetrics, etc:
Dissertation project
on hypoxia-induced craniofacial malformations in
chick embryos, included 2-D morphometric analysis of
images of hypoxic vs. normal embryos for abnormal
craniofacial variation (UCSF, 2007-2012)
3-D imaging by microCT
(for mouse and avian embryos and neonatal mouse
skulls) and by CT (for human faces) and morphometric
analysis of 3-D images for independent and
collaborative projects in mouse craniofacial
genetics and developmental biology, avian
evolutionary trajectories, and clinical studies of
craniofacial malformations (from clefts to
syndromes) (University of Calgary, 2012-2015) and
clinical projects that continued with collaborators
after this period |
Visiting research
experience at Hospital for Rehabilitation of
Craniofacial Anomalies in Bauru, Brazil, November
2017, assisting colleagues in volumetric and
morphological assessment of upper airway obstruction
in Treacher Collins syndrome via analysis of CT
images by volumetrics and morphometrics
Independent research
consulting to a University of Colorado Anschutz
Medical Center colleague in 3-D imaging and analysis
of dental samples for density, 2019-2020
Experience in
craniofacial embryology (mouse and chick embryos),
developmental biology, craniofacial biology, and
genetics:
-
2006-2007: King’s
College London, UK: analysis of expression
pattern of a novel gene in mouse embryos (2006)
and analysis of genetic regulation of
craniofacial myogenesis in chick embryos (2007)
-
2007: UCSF, first
PhD lab rotation: analysis of interaction
between oral squamous cell carcinoma cells and
surrounding extracellular matrix components
-
2008: UCSF, second
PhD lab rotation: assessment of hypoxia-induced
craniofacial malformations in chick embryos
(later evolved into dissertation project)
-
2009: UCSF, third
PhD lab rotation: examination of regulation of
avian embryonic mandibular bone growth and
development
-
2009-2012: UCSF,
PhD dissertation project: expanded assessment of
morphological changes and molecular and cellular
changes in response to hypoxia in chick embryos
resulting in craniofacial malformations
-
2015-2018:
University of Colorado Anschutz Medical Campus,
School of Dental Medicine, Department of
Craniofacial Biology: postdoctoral training and
experience in genomic and bioinformatic analysis
of comparative expression of craniofacial genes
among mouse embryonic craniofacial tissues
Contact Francis for a price quote |
